Neyro- i psikhotropnye effekty benzimidazola i ego proizvodnykh: Kniga prednaznachena dlya issledovateley v oblasti neyrofiziologii, farmakologii i biofiziki (Russian Edition)
Product details
| Management number | 233473896 | Release Date | 2026/06/27 | List Price | US$27.90 | Model Number | 233473896 | ||
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Vpervye s ispol'zovaniem metodov vnutrikletochnogo otvedeniya biopotentsialov i analiza krivykh pervoy proizvodnoy potentsialov deystviya bylo issledovano vliyanie benzimidazola i nekotorykh ego proizvodnykh na elektricheskuyu aktivnost' neyronov vinogradnoy ulitki. Pokazano, chto deystvie issledovannykh soedineniy zavisit ot ikh khimicheskoy struktury i tipa neyronov, membrany kotorykh obladayut vyrazhennoy spetsifichnost'yu, obuslovlennoy kharakternoy dlya kazhdogo tipa neyronov kombinatsiey ionnykh kanalov. Opredeleny porogovye , optimal'nye i toksicheskie kontsentratsii testiruemykh veshchestv. Ustanovleno, chto pri odnokratnom vnutribryushinnom vvedenii 50 mg/kg rastvora testiruemykh veshchestv odni proizvodnye aktiviruyut lokomotsiyu i psikhoemotsional'noe sostoyanie krys i, sledovatel'no, mogut obladat' psikhistimuliruyushchimi svoystvami, a drugie – ugnetayut dannye pokazateli, to est' obladayut antistressornm deystviem. V vysokikh dozakh 100 i 150 mg/kg vse issledovannye veshchestva generalizovano ugnetayut povedencheskie reaktsii zhivotnykh, okazyvaya moshchnoe sedetivnoe deystvie. Read more
| ISBN10 | 3846581178 |
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| ISBN13 | 978-3846581179 |
| Language | Russian |
| Publisher | LAP LAMBERT Academic Publishing |
| Dimensions | 5.91 x 0.29 x 8.66 inches |
| Item Weight | 7.1 ounces |
| Print length | 128 pages |
| Publication date | September 11, 2012 |
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Biochemistry
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